DNA Microarray Technology - Theory and Application
Bik-Kwoon Tye and Dave Lin

With the advent of the sequencing of the human genome, sequencing technologies have advanced to a state that complete nucleotide sequences of genomes of a wide spectrum of organisms and of individual humans can be determined at an affordable cost. We are moving from the genomics era (knowing the nucleotide sequences of whole genomes) to the functional genomics era (synthesizing information from whole genome sequences about the functions of genes). We will discuss microarray (gene chip) technologies that allow the global survey of genome-wide activities of genes under a given condition. The potential for application of these technologies is unlimited, allowing one to probe the interactions between genes within a genome and to correlate altered expression patterns of whole cells to disease states on a single chip.

This program will begin with a lecture presented by Dr. Tye and then Professor Dave Lin will take the students on a guided tour of the Microarray Facilities.